Increased serum high mobility group box-1 level in Churg-Strauss syndrome THIS ARTICLE HAS BEEN RETRACTED

Retraction. Increased serum vascular endothelial growth factor level in Churg-Strauss syndrome.

BACKGROUND Churg-Strauss syndrome (CSS) is a rare form of systemic vasculitis occurring in patients with asthma and hypereosinophilia. For optimal treatment, prompt distinction of CSS from asthma is necessary; however, there are few serologic screening markers for this purpose. Vascular endothelial growth factor (VEGF), a vascular permeability factor, has been associated with other systemic vas...

Churg-Strauss syndrome.

Churg-strauss syndrome.

First described in 1951 as an allergic and granulomatous angiitis, Churg-Strauss syndrome (CSS) is a small-vessel vasculitis. Mean age at the time of diagnosis is approximately 50 years, with a sex ratio around 1. Asthma is the central feature of CSS and precedes the systemic manifestations in almost all cases, whereas 70% of the patients have maxillary sinusitis, allergic rhinitis, and/or sinu...

Churg-Strauss Syndrome

Pulmonary: asthma, pneumonitis and haemoptysis. Upper respiratory tract: allergic rhinitis, paranasal sinusitis, nasal polyposis. Cardiac involvement is common. [6]This includes heart failure, myocarditis and myocardial infarction. [7] Skin: purpura, skin nodules, leukocytoclastic angiitis with palpable purpura, livedo reticularis, urticaria, necrotic bullae and digital ischaemia. Renal: glomer...

Churg-Strauss Syndrome

A 44 year old female nurse with a 20-year history of severe, steroid-dependent asthma, hypertension, hematuria, pleuritis, and sinusitis was referred from her ophthalmologist in January 2000, with the question of possible bilateral scleritis. The patient was treated with topical steroid (prednisolone acetate 6 times daily) for anterior uveitis, systemic prednisone (50mg per os) and steroid inha...